STUDY OF MECHANICAL EFFECTS OF LUMBAR DISC ARTHROPLASTY ON FACET JOINTS AT THE INDEX LEVEL/ADJACENT LEVELS BY USING A VALIDATED FINITE ELEMENT ANALYSIS

Introduction: Lumbar disc arthroplasty is a surgical procedure designed to treat degenerative disc disease by replacing the affected disc with a mobile prosthesis.Several types of implants fall under the term total disc replacement, such as ball-and-socket, mobile core or elastic prostheses.Some studies have shown that facet arthritis can develop a

Summary: Selective recruitment of protein kinases to the Hsp90 system is mediated by the adaptor co-chaperone Cdc37.We show that assembly of CDK4 and CDK6 into protein complexes is differentially regulated by the Cdc37-Hsp90 system.Like other Hsp90 kinase clients, binding of CDK4/6 to Cdc37 is blocked by ATP-competitive inhibitors.Cdc37-Hsp90 relin

The ubiquitous availability of genome sequencing data explains the Pillowsham Pair popularity of machine learning-based methods for the prediction of protein properties from their amino acid sequences.Over the years, while revising our own work, reading submitted manuscripts as well as published papers, we have noticed several recurring issues, whi

Converging evidence suggests close relationships between the action and social space representations.The concepts of peripersonal space, as defined by cognitive neuroscience, and interpersonal space, as defined by social psychology, refer to approximately the same spatial area surrounding our bodies.The Telescopic Antenna aim of this study was thus